We have developed novel 3D tissue models that accurately reflect the biology and function of human liver. Furthermore, we ANALYZED the pharmacogenomic landscape in 130,000 individuals and found that previously unappreciated rare genetic variants in drug metabolizing enzymes and transporters contribute 30-40% to differ inter-individual differences in drug response. Scientific Summary Background. Understanding human physiology, pharmacology […]
Erik Norberg was awarded a 2.3 million SEK project grant from Cancerfonden and a 6-year Young Investigator position from the same foundation. These grants are a direct continuation of his previous work supported focusing on understanding the metabolic regulation in cancer.